Malaria parasites must switch to sexual reproduction to infect mosquitoes, but how do they decide to become male or female? How does the same transcription factor make the switch and generate both sexes? Answers are emerging from our genetic screen Read More …
Our atlas of immune cells from Anopheles and Aedes mosquitoes is now available as a preprint from bioRxiv. Mosquito cellular immunity at single-cell resolution This very productive collaboration with the lab of Carolina Barillas-Mury at NIAID was led by our Read More …
The next PlasmoGEM screen is out! Taking >1300 mutants through the lifecycle, we discover many parasite genes essential at the liver stage and produce a stage-specific model of metabolism. An incredibly stimulating collaboration with our colleagues in the Heussler, Hazimanikatis, Read More …
We are delighted to have been awarded 30 mio kronor over 6 years by the Knut and Alice Wallenberg Foundation to screen for the genes in malaria parasite that are involved in mosquito transmission and study interaction with the mosquito Read More …
I am delighted that Umeå University has announced my appointment as future Director of the Laboratory for Molecular Infection Medicine Sweden (MIMS). Umeå University has since the very beginning of its 50-year history built a strong reputation in infectious disease Read More …
The lab has been awarded € 2.5 mio for genetic screens to identify Plasmodium berghei fertility genes at Umeå University. Sexual reproduction of malaria parasites is essential for their transmission by mosquitoes and it is expected that the funded project Read More …
The Billker lab has contributed to a paper in Elife which marks the lauch of the Malaria Cell Atlas by our colleages at the Sanger Institute. Adam Reid and Arthur Talmann are the lead authors and Mara Lawniczak is the Read More …
Cell Reports has today published our paper describing a rapid phosphoproteomic time course of the activated gametocytes. The analysis sheds new light on how transmission stages of malaria parasites respond rapidly to xanthurenic acid, the compound that signals their arrival Read More …
It has been a privilege to take our Wellcome Trust Advanced Course in Malaria Experimental Genetics to the University of Ghana this year. Co-directors were Drs. Ellen Bushell, Julian Rayner and Marcus Lee. We were impressed by a group of Read More …
We are delighted to announce the publication of the first genome scale screen in a malaria parasite in Cell. This paper is the culmination of many years of work by the PlasmoGEM team, led by Ellen Bushell, which started with Read More …